A multi-enzyme cascade for efficient production of d-p-hydroxyphenylglycine from l-tyrosine

In this study, a four-enzyme cascade pathway was developed and reconstructed in vivo for the production of d-p-hydroxyphenylglycine (D-HPG), a valuable intermediate used to produce β-lactam antibiotics and in fine-chemical synthesis, from l-tyrosine. In this pathway, catalytic conversion of the inte...

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Bibliographic Details
Main Authors: Chen, X. (Author), Gao, C. (Author), Liu, J. (Author), Liu, L. (Author), Song, W. (Author), Tan, X. (Author), Wu, J. (Author), Zhang, S. (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2021
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