Gene expression analysis in NSAID-induced rat small intestinal disease model with the intervention of berberine by the liquid chip technology

Objective: Investigate the effect and mechanism of berberine on the small intestinal mucosa of non-steroidal anti-inflammatory drugs (NSAIDs) related small intestinal injury. Materials and methods: Twenty-four SD rats were randomly divided into control group, model group and intervention group. The...

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Bibliographic Details
Main Authors:	Chao, G. (Author), Wang, Q. (Author), Ye, F. (Author), Zhang, S. (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2021
Subjects:	abdominal cavity animal experiment animal model animal tissue Article berberine Berberine calcitonin controlled study corticotropin releasing factor receptor 2 cyclic AMP diclofenac duodenum tissue female Gene gene expression profiling gene regulatory network heme oxygenase 1 high throughput sequencing histology ileocecal valve interleukin 1 interleukin 1beta interleukin 4 lamina propria liquid chip technology medical technology neuropeptide Y nonhuman NSAID-induced small intestinal disease proteinase activated receptor 2 proteinase activated receptor 4 purinergic P2X3 receptor rat serotonin serotonin 1A receptor serotonin 4 receptor serotonin receptor serotonin transporter small intestine disease small intestine mucosa sodium chloride The liquid chip technology vanilloid receptor 1 vasoactive intestinal polypeptide
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Gene expression analysis in NSAID-induced rat small intestinal disease model with the intervention of berberine by the liquid chip technology

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