PIG-A gene mutation as a genotoxicity biomaker in polycyclic aromatic hydrocarbon-exposed barbecue workers

PIG-A gene mutation as a genotoxicity biomaker in polycyclic aromatic hydrocarbon-exposed barbecue workers

Background: The PIG-A gene mutation assay is a valuable tool for measuring in vivo gene mutations in blood cells. The human PIG-A assay, used as a potential genotoxicity biomarker, is minimally invasive, sensitive, and cost-efficient; however, the relationship between carcinogen exposure and PIG-A m...

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Bibliographic Details
Main Authors: Cao, Y. (Author), Feng, N. (Author), Liu, W. (Author), Luan, Y. (Author), Tang, C. (Author), Wu, J. (Author), Xi, J. (Author), Yang, Z. (Author), You, X. (Author), Yu, Y. (Author), Zhang, X.Y (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
adult
Article
barbecue worker
controlled study
cytokinesis
erythrocyte
female
food service worker
gene
gene mutation
genetic association
genotoxicity
Genotoxicity
human
human cell
hydroxylation
lymphocyte
Lymphocyte cytokinesis-block micronucleus test
male
micronucleus test
middle aged
mutation rate
occupational exposure
occupational hazard
PIG A gene
PIG-A assay
polycyclic aromatic hydrocarbon
Polycyclic aromatic hydrocarbons
restaurant
risk assessment
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