A microRNA binding site polymorphism in the 3′ UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis

A microRNA binding site polymorphism in the 3′ UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis

Background: Vascular endothelial growth factor A (VEGF-A) plays an integral role in angiogenesis by contributing to growth, development, and metastasis of solid tumors. Recently, a single-nucleotide polymorphism +936C/T located in the VEGF-A 3′ untranslated region (UTR) facilitated the susceptibilit...

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Bibliographic Details
Main Authors: Johnson, T. (Author), Karuppasamy, N. (Author), Kontham, S.S (Author), Ramanathan, A. (Author), Shankaran, Z.S (Author), Walter, C.E.J (Author)
Format: Article
Language:English
Published: Springer Science and Business Media Deutschland GmbH 2022
Subjects:
+936C/T
3' untranslated region
3' Untranslated Regions
binding site
Binding Sites
case control study
Case-Control Studies
Colorectal cancer
Colorectal Neoplasms
colorectal tumor
ethnicity
Ethnicity
genetic predisposition
Genetic Predisposition to Disease
genetics
human
Humans
meta analysis
Meta-analysis
microRNA
MicroRNA polymorphisms
MicroRNAs
Polymorphism, Single Nucleotide
single nucleotide polymorphism
Vascular Endothelial Growth Factor A
vasculotropin A
VEGF-A
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