Pharmacokinetic-pharmacodynamic study of subcutaneous injection of depot nandrolone decanoate using dried blood spots sampling coupled with ultrapressure liquid chromatography tandem mass spectrometry assays

Pharmacokinetic-pharmacodynamic study of subcutaneous injection of depot nandrolone decanoate using dried blood spots sampling coupled with ultrapressure liquid chromatography tandem mass spectrometry assays

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Context: Testosterone (T) and nandrolone (N) esters require deep im injections by medical personnel but these often deposit injectate into sc fat so that more convenient sc self-administration may be feasible. Objective: To investigate the feasibility and pharmacology of sc injection of N decanoate...

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Bibliographic Details
Main Authors: Desai, R. (Author), Handelsman, D.J (Author), Jimenez, M. (Author), Singh, G.K.S (Author), Turner, L. (Author)
Format: Article
Language:English
Published: Endocrine Society 2014
Subjects:
adult
Adult
article
blood sampling
Blood Specimen Collection
capillary blood
Chromatography, Liquid
concentration response
controlled study
Delayed-Action Preparations
dried blood spot testing
Dried Blood Spot Testing
drug blood level
feasibility study
Follicle Stimulating Hormone
hematocrit
human
Humans
Injections, Subcutaneous
liquid chromatography
Luteinizing Hormone
male
Male
Nandrolone
nandrolone decanoate
normal human
plasma concentration-time curve
prick test
priority journal
room temperature
tandem mass spectrometry
Tandem Mass Spectrometry
testosterone
Testosterone
testosterone blood level
Young Adult
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