Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion in one of their eight viral RNAs (vRNAs) rendering them replication-incompetent. However, they c...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2021
|
| Subjects: | |
| Online Access: | View Fulltext in Publisher |