ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer

ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer

Immunotherapies provide effective treatments for previously untreatable tumors and identifying tumor-specific epitopes can help elucidate the molecular determinants of therapy response. Here, we describe a pipeline, ISOTOPE (ISOform-guided prediction of epiTOPEs In Cancer), for the comprehensive ide...

Full description

Bibliographic Details
Main Authors: Eyras, E. (Author), Fugmann, T. (Author), Pérez-Granado, J. (Author), Reixachs-Solé, M. (Author), Sanz, F. (Author), Trincado, J.L (Author), Yokota, J. (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
alternative RNA splicing
Alternative Splicing
Article
biological model
biology
Breast Neoplasms
breast tumor
cancer immunotherapy
Carcinoma, Small Cell
Cell Line, Tumor
Computational Biology
epitope
Epitopes
exon
female
Female
genetics
Histocompatibility Antigens Class I
HLA antigen class 1
human
Humans
immune checkpoint inhibitor
immunogenicity
immunology
immunotherapy
Immunotherapy
intron
isoprotein
Lung Neoplasms
lung tumor
major histocompatibility antigen class 1
male
Male
malignant neoplasm
mass spectrometry
melanoma
Melanoma
Models, Genetic
Models, Immunological
mutation
Mutation
neoplasm
Neoplasms
prediction
Protein Isoforms
RNA splicing
RNA Splicing
RNA-Seq
small cell carcinoma
software
somatic mutation
tumor cell line
tumor marker
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items