Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSCderived cardiomyocytes

Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSCderived cardiomyocytes

A better fundamental understanding of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has the potential to advance applications ranging from drug discovery to cardiac repair. Automated quantitative analysis of beating hiPSC-CMs is an important and fast developing component of...

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Bibliographic Details
Main Authors: Chen, C.S (Author), Lejeune, E. (Author), Zhang, K. (Author), Zhao, B. (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
Article
biological model
biology
cardiac muscle cell
cell component
cell culture
cell motion
cell population
cell structure
Cells, Cultured
Computational Biology
Cytological Techniques
cytology
human
human cell
Humans
image analysis
image processing
Image Processing, Computer-Assisted
image reconstruction
image segmentation
induced pluripotent stem cell
Induced Pluripotent Stem Cells
Models, Cardiovascular
Myocytes, Cardiac
physiology
procedures
quantitative analysis
sarcomere
sarcomere length
Sarcomeres
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