A conserved expression signature predicts growth rate and reveals cell & lineage-specific differences
Isogenic cells cultured together show heterogeneity in their proliferation rate. To determine the differences between fast and slow-proliferating cells, we developed a method to sort cells by proliferation rate, and performed RNA-seq on slow and fast proliferating subpopulations of pluripotent mouse...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |