ΔFBA-Predicting metabolic flux alterations using genome-scale metabolic models and differential transcriptomic data
Genome-scale metabolic models (GEMs) provide a powerful framework for simulating the entire set of biochemical reactions in a cell using a constraint-based modeling strategy called flux balance analysis (FBA). FBA relies on an assumed metabolic objective for generating metabolic fluxes using GEMs. B...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2021
|
| Subjects: | |
| Online Access: | View Fulltext in Publisher |