MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data
The growing number of next-generation sequencing (NGS) data presents a unique opportunity to study the combined impact of mitochondrial and nuclear-encoded genetic variation in complex disease. Mitochondrial DNA variants and in particular, heteroplasmic variants, are critical for determining human d...
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science
2021
|
Subjects: | |
Online Access: | View Fulltext in Publisher |