Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches
The Hippo-YAP/TAZ signaling pathway plays a critical role in tissue homeostasis, tumorigenesis, and degeneration disorders. The regulation of YAP/TAZ levels is controlled by a complex regulatory network, where several feedback loops have been identified. However, it remains elusive how these feedbac...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |