Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches
The Hippo-YAP/TAZ signaling pathway plays a critical role in tissue homeostasis, tumorigenesis, and degeneration disorders. The regulation of YAP/TAZ levels is controlled by a complex regulatory network, where several feedback loops have been identified. However, it remains elusive how these feedbac...
Main Authors: | Avila, D.B (Author), Melendez-Alvarez, J.R (Author), Tian, X.-J (Author) |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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