Engaging biological oscillators through second messenger pathways permits emergence of a robust gastric slow-wave during peristalsis

Engaging biological oscillators through second messenger pathways permits emergence of a robust gastric slow-wave during peristalsis

Peristalsis, the coordinated contraction—relaxation of the muscles of the stomach is important for normal gastric motility and is impaired in motility disorders. Coordinated electrical depolarizations that originate and propagate within a network of interconnected layers of interstitial cells of Caj...

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Bibliographic Details
Main Authors: Ahmed, M.A (Author), Jung, R. (Author), Venugopal, S. (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
animal
Animals
Article
Biological Clocks
biological model
biological rhythm
biology
calcium
Calcium
calcium ion
cell level
Computational Biology
electrical synapse
Electrical Synapses
feedback system
gastric dysmotility
gastrointestinal tract
Gastrointestinal Tract
human
Humans
innervation
inositol 1,4,5 trisphosphate
Inositol 1,4,5-Trisphosphate
inositol trisphosphate
interstitial cell of Cajal
Interstitial Cells of Cajal
intestine innervation
membrane potential
Membrane Potentials
metabolism
Models, Biological
muscle contraction
Muscle Contraction
Muscle, Smooth
peristalsis
Peristalsis
physiology
second messenger
Second Messenger Systems
simulation
smooth muscle
stomach motility
velocity
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