From decision to action: Detailed modelling of frog tadpoles reveals neuronal mechanisms of decision-making and reproduces unpredictable swimming movements in response to sensory signals

From decision to action: Detailed modelling of frog tadpoles reveals neuronal mechanisms of decision-making and reproduces unpredictable swimming movements in response to sensory signals

How does the brain process sensory stimuli, and decide whether to initiate locomotor behaviour? To investigate this question we develop two whole body computer models of a tadpole. The “Central Nervous System” (CNS) model uses evidence from whole-cell recording to define 2300 neurons in 12 classes t...

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Bibliographic Details
Main Authors: Borisyuk, R. (Author), Ferrario, A. (Author), Koutsikou, S. (Author), Li, W. (Author), Palyanov, A. (Author), Roberts, A. (Author), Soffe, S. (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
animal
animal behavior
Animals
Anura
Article
biological model
biology
Biomechanical Phenomena
biomechanics
Computational Biology
computer model
decision making
Decision Making
firing rate
larva
Larva
Models, Neurological
motor nerve
movement (physiology)
muscle innervation
nerve cell
nonhuman
patch clamp technique
Patch-Clamp Techniques
physiology
reticulospinal tract
rhombencephalon
Rhombencephalon
sensory memory
sensory stimulation
skin
skin stimulation
swimming
Swimming
tadpole
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