Motif-pattern dependence of biomolecular phase separation driven by specific interactions

Motif-pattern dependence of biomolecular phase separation driven by specific interactions

Eukaryotic cells partition a wide variety of important materials and processes into biomolecular condensates—phase-separated droplets that lack a membrane. In addition to nonspecific electrostatic or hydrophobic interactions, phase separation also depends on specific binding motifs that link togethe...

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Bibliographic Details
Main Authors: Meir, Y. (Author), Pyo, A.G.T (Author), Weiner, B.G (Author), Wingreen, N.S (Author)
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
animal
Animals
Article
biological activity
biological model
biology
Biophysical Phenomena
biophysics
cell separation
chemical bond
chemical phenomena
chemical structure
chemistry
Computational Biology
conformation
conformational transition
controlled study
diffusion
electrostatic precipitation
entropy
Entropy
eukaryotic cell
Eukaryotic Cells
Hydrophobic and Hydrophilic Interactions
hydrophobicity
intracellular space
Intracellular Space
metabolism
Models, Biological
Molecular Conformation
molecular interaction
molecular recognition
Monte Carlo method
Monte Carlo Method
nanolattice
phase separation
physiology
polymer
polymerization
Polymers
protein binding
Protein Binding
protein interaction
protein motif
RNA-binding domain
ubiquitin
viscosity
Viscosity
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