A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

Our understanding of how speed and persistence of cell migration affects the growth rate and size of tumors remains incomplete. To address this, we developed a mathematical model wherein cells migrate in two-dimensional space, divide, die or intravasate into the vasculature. Exploring a wide range o...

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Bibliographic Details
Main Authors: Fantini, D. (Author), Farhan, H. (Author), Ghannoum, S. (Author), Iyer, A. (Author), Köhn-Luque, A. (Author), Leoncio Netto, W. (Author), Mælandsmo, G.M (Author), Phuyal, S. (Author), Prasmickaite, L. (Author), Reiterer, V. (Author), Sengupta, D. (Author), Sørensen, Ø. (Author), Zahoor, M. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2023
Subjects:
Breast Neoplasms
breast tumor
female
Female
Golgi Apparatus
Golgi complex
Golgi matrix
Golgi Matrix Proteins
human
Humans
macrogolgin
membrane protein
Membrane Proteins
metabolism
pathology
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