Analysis of expression of vitamin E-binding proteins in H2O2induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction

Analysis of expression of vitamin E-binding proteins in H2O2induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction

Natural α-tocopherol (α-TCP), but not tocotrienol, is preferentially retained in the human body. α-Tocopherol transfer protein (α-TTP) is responsible for binding α-TCP for cellular uptake and has high affinity and specificity for α-TCP but not α-tocotrienol. The purpose of this study was to examine...

Full description

Bibliographic Details
Main Authors: Chang, S.K (Author), Chiroma, A.A (Author), Hamid, R.A (Author), Khaza'ai, H. (Author), Zainal, Z. (Author), Zakaria, Z.A (Author)
Format: Article
Language:English
Published: Public Library of Science, 2020
Subjects:
alpha tocopherol
alpha tocotrienol
alpha-Tocopherol
alpha-tocopherol transfer protein
antioxidant
Antioxidants
Article
bioavailability
Biological Availability
Biological Transport
carrier protein
Carrier Proteins
cell level
Cell Line, Tumor
controlled study
dietary supplement
Dietary Supplements
drug effect
gene
human
Humans
hydrogen peroxide
Hydrogen Peroxide
metabolism
nerve cell
Neurons
neuroprotective agent
Neuroprotective Agents
oxidative stress
Oxidative Stress
physiology
PI TPNA gene
protein expression
protein expression level
protein PI TPNA
protein SEC14L2
protein TTPA
SEC14L2 gene
secretion (process)
SK-N-SH cell line
Tocotrienols
transport at the cellular level
TTPA gene
tumor cell line
unclassified drug
vitamin binding protein
Vitamin E
vitamin metabolism
Online Access:View Fulltext in Publisher
View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Similar Items