Synthesis and structural analysis of persuasive antibacterial agents and enzyme inhibitors derived from 5-(1-(4-Tosyl)piperidin-4-yl)-1,3,4-oxadiazol-2-thiol

Due to outstanding biological activities of 1,3,4-oxadiazole, a series of S-substituted derivatives of 5-[1-(4-tosyl)piperidin-4-yl]-1,3,4-oxadiazol-2-thiol (5a-f) was synthesized. The reaction of p-toluene sulfonyl chloride (a) with ethyl isonepacotate (b) produced ethyl 1-(4-tosyl)piperidin-4-carb...

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Main Authors: Abbasi, M.A (Author), Ashraf, M. (Author), Aziz-Ur-Rehman (Author), Nazir, M. (Author), Raza, M.A (Author), Sattar, A. (Author), Shah, S.A.A (Author), Siddiqui, S.Z (Author)
Format: Article
Language:English
Published: Chemical Publishing Co. 2018
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