Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

OBJECTIVES: The anti-α4β7 integrin antibody vedolizumab (VDZ) is successfully used for the treatment of inflammatory bowel diseases. However, only a subgroup of patients respond to therapy. VDZ is administered at a fixed dose, leading to a wide range of serum concentrations in patients. Previous wor...

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Bibliographic Details
Main Authors: Atreya, I. (Author), Atreya, R. (Author), Becker, E. (Author), Müller, T.M (Author), Neurath, M.F (Author), Schweda, A. (Author), Ullrich, K.A.-M (Author), Voskens, C. (Author), Zundler, S. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Online Access:View Fulltext in Publisher