Galleria mellonella as an alternative in vivo model to study bacterial biofilms on stainless steel and titanium implants

Galleria mellonella as an alternative in vivo model to study bacterial biofilms on stainless steel and titanium implants

The purpose of this study was to establish an infection model of Galleria mellonella larvae as an alternative in vivo model for biofilm-associated infections on stainless steel and titanium implants. First, the model was established with sterile implants to evaluate biocompatibility. Titanium or sta...

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Bibliographic Details
Main Authors: Alagboso, F. (Author), Alt, V. (Author), Domann, E. (Author), Kampschulte, M. (Author), Kerschbaum, M. (Author), Mannala, G.K (Author), Pfeifer, C. (Author), Rupp, M. (Author), Sommer, U. (Author)
Format: Article
Language:English
Published: ALTEX Edition 2021
Subjects:
animal
animal experiment
animal model
animal tissue
Animals
antibiotic agent
antibiotic sensitivity
Article
autolysin
bacterial colonization
bacterial infection
bacterial load
bacterium contamination
bacterium isolation
biocompatibility
biofilm
Biofilms
bone mineralization
cell proliferation
colony formation
colony forming unit
controlled study
disease free survival
DNA isolation
electron microscopy
energy dispersive X ray spectroscopy
experimental Staphylococcus infection
Galleria mellonella
gene expression
gentamicin
hemolymph
immune response
implant inflammation
implantation
in vivo study
medical device contamination
methicillin resistant Staphylococcus aureus
methicillin resistant Staphylococcus aureus infection
micro-computed tomography
moth
Moths
nonhuman
real time reverse transcription polymerase chain reaction
RNA extraction
scanning electron microscopy
Smad anchor for receptor activation
stainless steel
Stainless Steel
Staphylococcus aureus
surface electron microscopy
titanium
Titanium
upregulation
wound healing
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