Performance of monocyte activation test supplemented with human serum compared to fetal bovine serum

The monocyte activation test (MAT) is used to detect pyrogens in pharmaceutical products and serves as replacement of the rabbit pyrogen test. The peripheral blood mononuclear cell-based MAT assay requires the addition of serum to the medium and is performed with either fetal bovine serum (FBS) or h...

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Bibliographic Details
Main Authors: Dieker, M. (Author), Doodeman, P. (Author), Gitz, E. (Author), Molenaar-De Backer, M.W.A (Author), ten Brinke, A. (Author)
Format: Article
Language:English
Published: ALTEX Edition 2021
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Online Access:View Fulltext in Publisher