RNA polymerase II clusters form in line with surface condensation on regulatory chromatin

RNA polymerase II clusters form in line with surface condensation on regulatory chromatin

It is essential for cells to control which genes are transcribed into RNA. In eukaryotes, two major control points are recruitment of RNA polymerase II (Pol II) into a paused state, and subsequent pause release toward transcription. Pol II recruitment and pause release occur in association with macr...

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Bibliographic Details
Main Authors: Hilbert, L. (Author), Klingberg, T. (Author), Kobitski, A.Y (Author), Mamontova, I. (Author), Nienhaus, G.U (Author), Noa, A. (Author), Pancholi, A. (Author), Prizak, R. (Author), Sobucki, M. (Author), Zaburdaev, V. (Author), Zhang, W. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
active matter
animal
animal experiment
animal model
Animals
Article
chromatin
Chromatin
controlled study
embryo
gene control
gene regulation
genetic transcription
genetics
metabolism
microscopy
nonhuman
nuclear organization
phase separation
RNA
RNA polymerase II
RNA Polymerase II
simulation
super-resolution microscopy
theoretical model
Transcription, Genetic
transcriptional condensates
zebra fish
Zebrafish
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