In silico, cytotoxic and antioxidant potential of novel ester, 3-hydroxyoctyl -5- trans-docosenoate isolated from anchusa arvensis (L.) m.bieb. against hepg-2 cancer cells

In silico, cytotoxic and antioxidant potential of novel ester, 3-hydroxyoctyl -5- trans-docosenoate isolated from anchusa arvensis (L.) m.bieb. against hepg-2 cancer cells

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Background: Cancer is one of the chronic health conditions worldwide. Various therapeutically active compounds from medicinal plants were the current focus of this research in order to uncover a treatment regimen for cancer. Anchusa arvensis (A. anchusa) (L.) M.Bieb. contains many biologically activ...

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Bibliographic Details
Main Authors: Ali Shah, S.A (Author), Aman, W. (Author), Ayaz, M. (Author), Hussain, S. (Author), Nasr, F.A (Author), Shah, A.-U.-H.A (Author), Shah, S.M (Author), Shahat, A.A (Author), Ullah, F. (Author), Ullah, R. (Author), Wadood, A. (Author)
Format: Article
Language:English
Published: Dove Medical Press Ltd. 2019
Subjects:
1,1-diphenyl-2-picrylhydrazyl
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
3 hydroxyoctyl 5 docosenoate
3-hydroxyoctyl-5
ABTS radical scavenging assay
Anchusa arvensis
animal
Animals
antineoplastic activity
antineoplastic agent
Antineoplastic Agents, Phytogenic
antioxidant
Antioxidant
antioxidant activity
Antioxidants
Article
ascorbic acid
benzothiazole derivative
Benzothiazoles
Biphenyl Compounds
biphenyl derivative
Boraginaceae
Cancer
cell proliferation
Cell Proliferation
chemical structure
chemistry
Chlorocebus aethiops
computer model
computer simulation
Computer Simulation
controlled study
Cytotoxicity against HepG-2 cell lines
dose response
Dose-Response Relationship, Drug
doxorubicin
DPPH radical scavenging assay
drug cytotoxicity
drug effect
drug isolation
drug screening
Drug Screening Assays, Antitumor
drug structure
ester
Esters
Fatty Acids, Monounsaturated
Hep G2 Cells
Hep-G2 cell line
human
human cell
Humans
hydrogen bond
IC50
in vitro study
isolation and purification
liver cell carcinoma
medicinal plant
molecular docking
Molecular Docking Simulation
Molecular Structure
monounsaturated fatty acid
Picrates
picric acid
plant medicinal product
Plants, Medicinal
structure activity relation
Structure-Activity Relationship
sulfonic acid derivative
Sulfonic Acids
Trans-docosenoate
unclassified drug
Vero cell line
Vero Cells
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