Structure–activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives

This paper presents the synthesis of some unique bi-heterocyclic hybrid molecules with a thiazole and an oxadiazole ring. The synthesis was initiated by the conversion of ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate (1) to the corresponding 2-(2-amino-1,3-thiazol-4-yl)acetohydrazide (2) by the reaction...

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Main Authors: Abbasi, M.A (Author), Aziz-Ur-Rehman (Author), Hassan, M. (Author), Mirza, B. (Author), Ramzan, M.S (Author), Raza, H. (Author), Seo, S.-Y (Author), Shah, S.A.A (Author), Siddiqui, S.Z (Author)
Format: Article
Language:English
Published: Serbian Chemical Society 2019
Subjects:
1
3
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