Hypoxia-induced upregulation of angiogenic factors in immortalized human periodontal ligament fibroblasts

Hypoxia-induced upregulation of angiogenic factors in immortalized human periodontal ligament fibroblasts

Hypoxia induces complex cellular responses that are mediated by a key transcription factor, hypoxia-inducible factor-1 (HIF-1). HIF-1 promotes production of cytokines and angiogenic factors and contributes to recovery of injured tissues. In the present study, expressions of angiogenin (ANG) and vasc...

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Bibliographic Details
Main Authors: Asano, M. (Author), Hasegawa, T. (Author), Ishiyama, M. (Author), Ito, H. (Author), Iwasa, S. (Author), Kifune, T. (Author), Shirakawa, T. (Author), Takei, H. (Author)
Format: Article
Language:English
Published: Nihon University, School of Dentistry 2018
Subjects:
angiogenin
Angiogenin
Blotting, Western
cell culture
cell line
Cell Line
Cells, Cultured
cytokine
Cytokines
cytology
fibroblast
Fibroblasts
fluorescent antibody technique
Fluorescent Antibody Technique
HIF-1
human
Humans
hypoxia
Hypoxia
hypoxia inducible factor 1
Hypoxia-Inducible Factor 1
messenger RNA
metabolism
pancreatic ribonuclease
periodontal ligament
Periodontal Ligament
Periodontal ligament fibroblasts
real time polymerase chain reaction
Real-Time Polymerase Chain Reaction
Ribonuclease, Pancreatic
RNA, Messenger
upregulation
Up-Regulation
Vascular endothelial growth factor
Vascular Endothelial Growth Factor A
vasculotropin A
Western blotting
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