Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

Epigenetic regulation is an important factor in glucose metabolism, but underlying mechanisms remain largely unknown. Here we investigated epigenetic control of systemic metabolism by bromodomain-containing proteins (Brds), which are transcriptional regulators binding to acetylated histone, in both...

Full description

Bibliographic Details
Main Authors: Aguayo-Mazzucato, C. (Author), Alonso-Curbelo, D. (Author), Carapeto, P. (Author), Chimene-Weiss, J. (Author), Desmond, J. (Author), Efthymiou, V. (Author), Gerszten, R.E (Author), Goodyear, L. (Author), Isganaitis, E. (Author), Kozuka, C. (Author), Kusuyama, J. (Author), Mulla, C. (Author), Osataphan, S. (Author), Patti, M.-E (Author), Qi, J. (Author), Sales, V.M (Author), Sandoval, D. (Author), Sanechika, S. (Author), Shi, X. (Author), Teixeira, S.D (Author), Wu, L. (Author), Yuchi, Y. (Author), Zhou, L. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Online Access:View Fulltext in Publisher