Alteration of the Individual Metabolic Network of the Brain Based on Jensen-Shannon Divergence Similarity Estimation in Elderly Patients With Type 2 Diabetes Mellitus

Alteration of the Individual Metabolic Network of the Brain Based on Jensen-Shannon Divergence Similarity Estimation in Elderly Patients With Type 2 Diabetes Mellitus

The aim of this study was to investigate the interactive effect between aging and type 2 diabetes mellitus (T2DM) on brain glucose metabolism, individual metabolic connectivity, and network properties. Using a 2 × 2 factorial design, 83 patients with T2DM (40 elderly and 43 middle-aged) and 69 sex-m...

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Bibliographic Details
Main Authors: Hua, X.-Y (Author), Li, S.-S (Author), Li, Y.-L (Author), Ma, J. (Author), Shan, C.-L (Author), Wei, D. (Author), Wu, J.-J (Author), Xu, J.-G (Author), Xue, X. (Author), Zheng, M.-X (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
aged
Aged
brain
Brain
Diabetes Mellitus, Type 2
fluorodeoxyglucose f 18
Fluorodeoxyglucose F18
glucose
Glucose
human
Humans
Magnetic Resonance Imaging
Metabolic Networks and Pathways
metabolism
middle aged
Middle Aged
non insulin dependent diabetes mellitus
nuclear magnetic resonance imaging
positron emission tomography
Positron-Emission Tomography
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