YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells

To date, identification of nonislet-specific transcriptional factors in the regulation of insulin gene expression has been little studied. Here, we report that the expression level of the transcription factor YY1 is increased dramatically in both human and mouse pancreatic β-cells after birth. Never...

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Bibliographic Details
Main Authors: Chan, V.W (Author), Cheng, K.K.Y (Author), Chong, C.C.N (Author), Liu, D. (Author), Lui, K.O (Author), Wang, C.C (Author), Wang, H. (Author), Yang, K.Y (Author), Ye, W. (Author), Zhou, B. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
animal
Animals
diabetes mellitus
Diabetes Mellitus
genetics
glucose
Glucose
homeostasis
Homeostasis
human insulin
insulin
Insulin
Insulin, Regular, Human
Insulin-Secreting Cells
metabolism
Mice
mouse
pancreas islet beta cell
transcription factor YY1
YY1 Transcription Factor
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