Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

C-peptide declines in type 1 diabetes, although many long-duration patients retain low, but detectable levels. Histological analyses confirm that β-cells can remain following type 1 diabetes onset. We explored the trends observed in C-peptide decline in the UK Genetic Resource Investigating Diabetes...

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Bibliographic Details
Main Authors: Besser, R.E.J (Author), Carr, A.L.J (Author), Dunger, D.B (Author), Flaxman, C.S (Author), Hull, B. (Author), Inshaw, J.R.J (Author), Leete, P. (Author), Morgan, N.G (Author), Oram, R.A (Author), Palmer, M. (Author), Prasolov, D. (Author), Richardson, S.J (Author), Russell, L.A (Author), Todd, J.A (Author), Wicker, L.S (Author), Worthington, T. (Author), Wyatt, R.C (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
adolescent
Adolescent
C peptide
child
Child
C-Peptide
Diabetes Mellitus, Type 1
donor
genetics
human
Humans
infant
Infant
insulin dependent diabetes mellitus
Insulin-Secreting Cells
pancreas
Pancreas
pancreas islet beta cell
pathology
Tissue Donors
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