Synthesis and structure-activity relationship of 1-[(E)-3-phenyl-2-propenyl] piperazine derivatives as suitable antibacterial agents with mild hemolysis
A new series of 1-[(E)-3-phenyl-2-propenyl]piperazine derivatives (5a-m) as antibacterial agents was designed and synthesized. The synthetic strategy was initiated by coupling different anilines (1a-m) with bromoacetyl bromide (2) in an aqueous basic medium to acquire different electrophiles, 3a-m,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sharif University of Technology
2019
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| Subjects: | |
| Online Access: | View Fulltext in Publisher View in Scopus |