Concise strategy for diastereoselective annulation to afford fused [5:7] oxazepanone γ-lactams

A series of novel potentially biologically active fused [5:7] oxazepanone γ-lactams were synthesized and described. A series of functional group transformations, namely amination, syn-hydrogenation and intramolecular annulation reactions were used to obtain the [5:7] oxazepanone γ-lactams in reasona...

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Bibliographic Details
Main Authors: Hamzah, A.S (Author), Mansor, N.S (Author), Mohammat, M.F (Author), Rashid, F.N.A.A (Author), Shaameri, Z. (Author)
Format: Article
Language:English
Published: Arkat 2021
Series:Arkivoc
Subjects:
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