Tpc1 and tpc2 promote osteoclastogenesis
Osteoclast differentiation is one of the key steps that regulate bone mass and involves RANKL-induced changes in the intracellular Ca2+ levels. Previously, we reported the function of a lysosomal Ca2+ channel, two-pore channel (TPC) subtype 2 (TPC2), using TPC2-knockout RAW264.7 cell line (RAW) duri...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Society of Hard Tissue Regenerative Biology
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |