Tpc1 and tpc2 promote osteoclastogenesis

Osteoclast differentiation is one of the key steps that regulate bone mass and involves RANKL-induced changes in the intracellular Ca2+ levels. Previously, we reported the function of a lysosomal Ca2+ channel, two-pore channel (TPC) subtype 2 (TPC2), using TPC2-knockout RAW264.7 cell line (RAW) duri...

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Bibliographic Details
Main Authors: Ezura, Y. (Author), Kawazoe, T. (Author), Kise, C. (Author), Kobayashi, R. (Author), Momota, Y. (Author), Notomi, T. (Author), Otsuka, M. (Author)
Format: Article
Language:English
Published: Society of Hard Tissue Regenerative Biology 2021
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