Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

Mitochondrial homeostasis is tightly controlled by ubiquitination. The mitochondrial integral membrane ubiquitin ligase MARCH5 is a crucial regulator of mitochondrial membrane fission, fusion, and disposal through mitophagy. In addition, the lipid composition of mitochondrial membranes can determine...

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Bibliographic Details
Main Authors: Bauer, J. (Author), Damgaard, R.B (Author), Merklinger, L. (Author), Morth, J.P (Author), Pedersen, P.A (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
cardiolipin
Cardiolipins
membrane protein
Membrane Proteins
metabolism
mitochondrial membrane
Mitochondrial Membranes
mitochondrial protein
Mitochondrial Proteins
phospholipid
Phospholipids
ubiquitin
Ubiquitin
ubiquitin protein ligase
Ubiquitin-Protein Ligases
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