Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans

Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans

In the human fungal pathogen Candida albicans, ARO1 encodes an essential multi-enzyme that catalyses consecutive steps in the shikimate pathway for biosynthesis of chorismate, a precursor to folate and the aromatic amino acids. We obtained the first molecular image of C. albicans Aro1 that reveals t...

Full description

Bibliographic Details
Main Authors: Borek, D. (Author), Cowen, L.E (Author), Evdokimova, E. (Author), Liston, S.D (Author), Michalska, K. (Author), Otwinowski, Z. (Author), Quade, B. (Author), Ram, S. (Author), Savchenko, A. (Author), Semper, C. (Author), Stogios, P.J (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items