A Reactive Oxygen Species-Tyrosinase Cascade- Activated Prodrug for Selectively Suppressing Melanoma
"Off-target effect" is one of the obstacles for targeted prodrugs in chemotherapy. To circumvent this issue, herein we propose a dual biomarker cascadeactivated prodrug strategy based on high levels of reactive oxygen species (ROS) and tyrosinase (TYR) in melanoma cells. A representative p...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Chinese Chemical Society
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |