A Reactive Oxygen Species-Tyrosinase Cascade- Activated Prodrug for Selectively Suppressing Melanoma
"Off-target effect" is one of the obstacles for targeted prodrugs in chemotherapy. To circumvent this issue, herein we propose a dual biomarker cascadeactivated prodrug strategy based on high levels of reactive oxygen species (ROS) and tyrosinase (TYR) in melanoma cells. A representative p...
Main Authors: | Huang, J. (Author), Huang, P. (Author), Li, G. (Author), Song, Z. (Author), Yan, J. (Author), Yang, Y. (Author), Yuan, Q. (Author), Zhang, Y. (Author) |
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Format: | Article |
Language: | English |
Published: |
Chinese Chemical Society
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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