Synthesis of Dihydroisoquinoline and Dihydropyridine Derivatives via Asymmetric Dearomative Three-Component Reaction
We report the first asymmetric three-component nucleophilic addition/dearomative [4+2] cycloaddition/isomerization cascade of transient dipoles generated from N-heteroarenes and allenoates with methyleneindolinones in the presence of chiral N,N′-dioxide/metal complexes. This tandem reaction enabled...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Chinese Chemical Society
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |