REGIO-AND STEREOSELECTIVITY OF 1,3-DIPOLAR CYCLOADDITION REACTION OF CINNARIZINE DRUG WITH CHIRAL NITRONES, AND THEIR ANTIMICROBIAL ACTIVITY
2-Methyl-3-(Aryl)-4(phenyl)-5-(1-methylene-4-diphenylmethylpiperazine) isoxazolidine (3a-j) have been prepared by 1,3-dipolar cycloaddition reaction of the synthesized C-aryl-N-methylnitrones (1a-j) with Cinnarizine and some physical properties (melting points (m.p), Retardation Factor (Rf), etc) th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |