Acupuncture improves learning and memory ability of posttraumatic stress disorder model rats through epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway

Acupuncture improves learning and memory ability of posttraumatic stress disorder model rats through epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway

BACKGROUND: Microglia express phosphatidylinositol 3-kinase (PI3K) has been implicated in the induction and maintenance of long-term potentiation (LTP) and in hippocampal synaptic plasticity. However, there are few studies on the interference of PI3K signal pathway in microglia. OBJECTIVE: The study...

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Bibliographic Details
Main Authors: Jiang, Y. (Author), Li, K. (Author), Li, M. (Author), Wang, X. (Author), Xie, Y. (Author), Yang, L. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2023
Subjects:
animal
Animals
brain derived neurotrophic factor
Brain-Derived Neurotrophic Factor
electroacupuncture
Electroacupuncture
Epigenesis, Genetic
genetic epigenesis
long intergenic noncoding RNAs
long-term potentiation
metabolism
microglia
Microglia
phosphatidylinositol 3 kinase
Phosphatidylinositol 3-Kinase
Phosphatidylinositol 3-Kinases
posttraumatic stress disorder
protein ubiquitination
PTSD
rat
Rats
Stress Disorders, Post-Traumatic
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