Comparing Efficacy and Safety of Empirical vs. Guided Therapy for Non-cardiac Chest Pain: A Pragmatic Randomized Trial

Comparing Efficacy and Safety of Empirical vs. Guided Therapy for Non-cardiac Chest Pain: A Pragmatic Randomized Trial

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Background: Non-cardiac chest pain is common with two-thirds due to gastroesophageal reflux disease (GERD). Objective: To evaluate the effectiveness and safety of guided vs. empirical therapy in non-cardiac chest pain. Methods: Adults with normal angiogram or stress test were randomized into either...

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Bibliographic Details
Main Authors: Abd Aziz, A. (Author), Abdul Hafidz, M.I (Author), Abdul Kadir, N.P (Author), Annamalai, C. (Author), Hamid, N. (Author), Jayaraman, T. (Author), Lee, H. (Author), Lee, Y.Y (Author), Ma, Z.F (Author), Norhasliza, S. (Author), Yusof, Z. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Series:Frontiers in Medicine
Subjects:
abdominal pain
adult
ambulatory monitoring
Article
body mass
comparative effectiveness
controlled study
dexlansoprazole
dyspepsia
female
gastroesophageal reflux
GERD (gastroesophageal reflux disease)
heart palpitation
human
intention to treat analysis
maculopapular rash
major clinical study
male
manometry
noncardiac chest pain
non-cardiac chest pain
outcome assessment
practice guideline
quality of life
randomized controlled trial
reflux esophagitis
theophylline
visual analog scale
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