Anatomical and Functional Characterization of Central Amygdala Glucagon-Like Peptide 1 Receptor Expressing Neurons

Anatomical and Functional Characterization of Central Amygdala Glucagon-Like Peptide 1 Receptor Expressing Neurons

Glucagon-like peptide 1 receptors (GLP-1Rs) are highly expressed in the brain and are responsible for mediating the acute anorexigenic actions of widely prescribed GLP-1R agonists. Neurobiological efforts to localize the hypophagic effects of GLP-1R agonists in the brain have mainly focused on the h...

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Bibliographic Details
Main Authors: Cutts, E.J (Author), Duran, M. (Author), Hardaway, J.A (Author), Kaur, S. (Author), Lopez, C.B (Author), Virkus, S.A (Author), Zeng, N. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
anatomy
animal experiment
animal tissue
Article
brain electrophysiology
brain level
cell membrane conductance
cell subpopulation
central amygdala (CeA)
central nucleus (amygdala)
controlled study
electrophysiology
female
gene
Glp1r gene
glucagon like peptide 1 receptor
glucagon-like peptide 1 (GLP-1)
glucagon-like peptide 1 receptor (GLP-1R)
histopathology
hyperpolarization
male
mouse
mRNA expression level
nerve cell stimulation
neural circuit
neurophysiology
nonhuman
Prkcd gene
protein kinase C delta
sex difference
somatostatin receptor
Sst gene
Tac2 gene
tachykinin receptor
transport at the cellular level
whole cell patch clamp
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