Chronic Social Defeat During Adolescence Induces Short- and Long-Term Behavioral and Neuroendocrine Effects in Male Swiss-Webster Mice

Chronic Social Defeat During Adolescence Induces Short- and Long-Term Behavioral and Neuroendocrine Effects in Male Swiss-Webster Mice

Chronic stress exposure during adolescence is a significant risk factor for the development of depression. Chronic social defeat (CSD) in rodents is an animal model of depression with excellent ethological, predictive, discriminative, and face validity. Because the CSD model has not been thoroughly...

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Bibliographic Details
Main Authors: Estrada-Camarena, E. (Author), López-Pacheco, E. (Author), López-Rubalcava, C. (Author), Mancha-Gutiérrez, H.M (Author), Mayagoitia-Novales, L. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
adolescence
adolescent
adolescent behavior
adrenal cortex
adulthood
aging
animal experiment
animal model
animal tissue
Article
autoradiography
Barnes maze test
brain development
chronic social defeat
cognition
cognitive defect
controlled study
corticosterone
corticosterone blood level
depression
forced swim test
gonad function
hippocampus
immobility
long term behavior
male
memory disorder
mouse
neuroendocrine regulation
nonhuman
perinatal period
protein binding
serotonin transporter
social avoidance behavior
social defeat
social interaction test
social stress
stress
testosterone
testosterone blood level
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