Disrupted functional connectivity of cornu ammonis subregions in amnestic mild cognitive impairment: A longitudinal resting-state fMRI study

Disrupted functional connectivity of cornu ammonis subregions in amnestic mild cognitive impairment: A longitudinal resting-state fMRI study

Background: The cornu ammonis (CA), as part of the hippocampal formation, represents a primary target region of neural degeneration in amnestic mild cognitive impairment (aMCI). Previous studies have revealed subtle structural deficits of the CA subregions (CA1-CA3, bilateral) in aMCI; however, it i...

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Bibliographic Details
Main Authors: Fan, X. (Author), Jia, X. (Author), Li, C.-S.R (Author), Li, H. (Author), Li, K. (Author), Lu, J. (Author), Ma, T. (Author), Ni, H. (Author), Pang, R. (Author), Qi, Z. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2018
Subjects:
aged
amnesia
Amnestic mild cognitive impairment
Article
brain size
clinical article
controlled study
Cornu ammonis
correlational study
educational status
episodic memory
female
follow up
functional connectivity
Functional connectivity
functional magnetic resonance imaging
gender
gray matter
groups by age
hippocampal CA1 region
hippocampal CA2 region
hippocampus
Hippocampus
human
Longitudinal study
male
mental performance
middle temporal gyrus
mild cognitive impairment
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