Neurodegeneration and Vascular Burden on Cognition After Midlife: A Plasma and Neuroimaging Biomarker Study

Neurodegeneration and Vascular Burden on Cognition After Midlife: A Plasma and Neuroimaging Biomarker Study

Background and Objectives: Neurodegeneration and vascular burden are the two most common causes of post-stroke cognitive impairment. However, the interrelationship between the plasma beta-amyloid (Aβ) and tau protein, cortical atrophy and brain amyloid accumulation on PET imaging in stroke patients...

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Bibliographic Details
Main Authors: Chang, T.-Y (Author), Chang, Y.-J (Author), Ho, M.-Y (Author), Hsiao, I.-T (Author), Huang, K.-L (Author), Lee, T.-H (Author), Lin, K.-J (Author), Liu, C.-H (Author), Wu, H.-C (Author), Wu, Y.-M (Author), Yang, S.-Y (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
adult
age
amyloid
amyloid beta protein[1-40]
amyloid beta protein[1-42]
amyloid plaque
Article
biological marker
cerebrovascular accident
clinical article
Clinical Dementia Rating
cognition
controlled study
cortical thickness (brain)
cross-sectional study
female
florbetapir f 18
Geriatric Depression Scale
human
ischemic stroke
male
middle aged
Mini Mental State Examination
nerve degeneration
neuroimaging
nuclear magnetic resonance imaging
onset age
PET
plasma biomarker
positron emission tomography
post-stroke cognitive impairment
prospective study
protein blood level
tau protein
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