Prognostic Factors and Survival Benefits of Antitumor Treatments for Advanced Non-Small Cell Lung Cancer Patients With Central Nervous System Metastasis With or Without Driver Genes: A Chinese Single-Center Cohort Study

Prognostic Factors and Survival Benefits of Antitumor Treatments for Advanced Non-Small Cell Lung Cancer Patients With Central Nervous System Metastasis With or Without Driver Genes: A Chinese Single-Center Cohort Study

Background: The prognosis of non-small cell lung cancer (NSCLC) patients with central nervous system (CNS) metastasis is poor. The treatment for CNS metastasis could prolong the overall survival of NSCLC patients. We aimed to investigate the prognostic factors of Chinese NSCLC patients with CNS meta...

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Bibliographic Details
Main Authors: Chen, M. (Author), Gao, X. (Author), Liang, H. (Author), Liu, X. (Author), Pan, R. (Author), Shi, Y. (Author), Wang, M. (Author), Xu, Y. (Author), Zhao, J. (Author), Zhong, W. (Author), Zhou, Q. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
adult
alectinib
anaplastic lymphoma kinase
Article
bevacizumab
brain surgery
cancer patient
cancer prognosis
cancer radiotherapy
cancer staging
cancer therapy
central nervous system metastasis
ceritinib
chemotherapy
Chinese
cohort analysis
cohort study
computer assisted tomography
controlled study
crizotinib
driver gene
ECOG Performance Status
epidermal growth factor receptor
erlotinib
female
fluorescence in situ hybridization
follow up
gefitinib
gene
gene mutation
gene rearrangement
human
human tissue
icotinib
immunohistochemistry
lung adenocarcinoma
major clinical study
male
middle aged
non small cell lung cancer
non-small-cell lung cancer
nuclear magnetic resonance imaging
oncogene ret
osimertinib
overall survival
prognostic factors
retrospective study
risk factor
scatter factor receptor
survival time
treatment outcome
whole brain radiotherapy
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