Amyloid-β Induces Cdh1-Mediated Rock2 Stabilization Causing Neurodegeneration

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, which is causally related to the accumulation of abnormally folded amyloid-β (Aβ) peptide and hyperphosphorylated tau protein aggregates. The dendritic spine regulator Rho protein kinase 2 (Rock2...

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Bibliographic Details
Main Authors: Agulla, J. (Author), Almeida, A. (Author), Bolaños, J.P (Author), Gonzalez-Guerrero, S. (Author), Lapresa, R. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
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Online Access:View Fulltext in Publisher