Responsivity of the Striatal Dopamine System to Methylphenidate—A Within-Subject I-123-β-CIT-SPECT Study in Male Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

Responsivity of the Striatal Dopamine System to Methylphenidate—A Within-Subject I-123-β-CIT-SPECT Study in Male Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

Background: Methylphenidate (MPH) is the first-line pharmacological treatment of attention-deficit/hyperactivity disorder (ADHD). MPH binds to the dopamine (DA) transporter (DAT), which has high density in the striatum. Assessments of the striatal dopamine transporter by single positron emission com...

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Bibliographic Details
Main Authors: Andreatta, M. (Author), Aster, H.-C (Author), Buck, A.K (Author), Deserno, L. (Author), Gerlach, M. (Author), Hartrampf, P.E (Author), Hasenauer, N. (Author), Lorenz, R. (Author), Mühlberger, A. (Author), Nerlich, K. (Author), Reiners, C. (Author), Rizzo, A. (Author), Romanos, M. (Author), Walitza, S. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2022
Subjects:
attention deficit/hyperactivity disorder (ADHD)
caudate nucleus
dopamine transporter (DAT)
methylphenidate
responsivity
single photon emission computed tomography (SPECT)
striatum
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