Whole‐Exome Sequencing of Germline Variants in Non‐BRCA Families with Hereditary Breast Cancer

Whole‐Exome Sequencing of Germline Variants in Non‐BRCA Families with Hereditary Breast Cancer

Breast cancer is the most prevalent malignancy among women worldwide and hereditary breast cancer (HBC) accounts for about 5–10% of the cases. Today, the most recurrent genes known are BRCA1 and BRCA2, accounting for around 25% of familial cases. Although thousands of loss-of‐function variants in mo...

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Bibliographic Details
Main Authors: Bajalica‐lagercrantz, S. (Author), Choi, J. (Author), Helgadottir, H.T (Author), Höiom, V. (Author), Juhlin, C.C (Author), Kharaziha, P. (Author), Larsson, C. (Author), Liu, Y. (Author), López‐giráldez, F. (Author), Mane, S.M (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
bioinformatics
germline variants
hereditary breast cancer
whole‐exome sequencing
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