Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts

Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts

Pancreatic cancer is a devastating disease and is highly resistant to anticancer drugs because of its complex microenvironment. Cancer-associated fibroblasts (CAFs) are an important source of extracellular matrix (ECM) components, which alter the physical and chemical properties of pancreatic tissue...

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Bibliographic Details
Main Authors: Ahn, J.M (Author), Bae, W.J (Author), Cho, C.-H (Author), Choi, W.H (Author), Go, Y.-H (Author), Jung, S.-I (Author), Kim, S.W (Author), Lee, D. (Author), Lee, K.J (Author), Lee, S.A (Author), Park, J.S (Author), Yoo, J. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
cancer-associated fibroblast
extracellular matrix
organoid
pancreatic cancer
tumor microenvironment
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