LPIN1 Induces Gefitinib Resistance in EGFR Inhibitor-Resistant Non-Small Cell Lung Cancer Cells

Drug resistance limits the efficacy of targeted therapies, including tyrosine kinase inhibitors (TKIs); however, a substantial portion of the drug resistance mechanisms remains unexplained. In this study, we identified LPIN1 as a key factor that regulates gefitinib resistance in epidermal growth fac...

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Bibliographic Details
Main Authors: Cho, J.H (Author), Koo, H. (Author), Lee, D.C (Author), Park, K.C (Author), Yeom, Y.I (Author), You, Y.-M (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher